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Research

The EHA Clinics Research team, led by our Chief Innovation Officer, works with scientists and research organisations to design and implement research projects in Nigeria and other African countries

Our team handles holistic research

Our team can support the development of research protocols that can be implemented effectively in resource-constrained environments and can manage all study operations, logistics, and data management. Additionally, EHA Clinics can support getting all necessary ethical approvals for research based in Nigeria, ensuring the safety of human subjects.

We also operate a Health Research Ethics Committee registered under the Nigerian National Health Research Ethics Committee for review of study protocols.

our research areas

Our team focuses on the following research areas

Laboratory &
Diagnostice

Chronic
Disease

Genomics
Research

Health & Behavioural Economics

Medical Device Development

We have received over ten national and international grants resulting in multiple peer-reviewed publications.

Get in touch

Electronic Health Records/mHealth

Community Health Research

Infectious Diseases & Neglected Tropical Diseases

our work

‍Research publications and presentations

2023, Evaluating the impact of mass media awareness campaigns on the prevention of Lassa fever spread in rural communities of Kano State

Oluwaseunayo Deborah Ayando, Nirmal Ravi, Adham Hallal, Margaret AlabiGET Conference 2023 - Hosted by the Global Emerging Pathogens Treatment Consortium, Lagos, Nigeria.

2023 Transitioning from Traditional EMR to Open EHR: A Case Study of the Impact on Clinical Workflows, Potential for Data Interoperability and Quality Improvement Initiatives

George Ohia, Adham Hallal, Nirmal Ravi, Adam Thompson. November, 2023.HELINA Conference 2023 - Hosted by the South African Health Informatics Association (SAHIA), Cape Town, South Africa.

2023 Unmet need for online CPD training of laboratorians

Oluwaseunayo Deborah Ayando, Nirmal Ravi, Okoronkwo Marizu ObinnayaCelebrate Lab Conference 2023 - Hosted by Africabio Enterprises, Abuja, Nigeria.

2023 Construction of a Multiple Epitope Vaccine Against H3N8 Strain of Avian Influenza: A Bioinformatics Approach

Chimenya H. Ntweya, Ojochenemi A. Enejoh,Margaret A. Oyekunle,Anjellina Rukundo, Adham Hallal,Oudou Diabate, Deborah O. Ayando,Eniola Onabowale and Olaitan I. Awe.OMICS Codeathon 2023 - Hosted by the African Society for Bioinformatics and Computational Biology (ASBCB).

2022 Development and Validation of Manually Modified and Supervised Machine Learning Clinical Assessment Algorithms for Malaria in Nigerian Children

Megan McLaughlin, Karrel G. Pelle, Samuel V. Scarpino, Aisha Giwa, Ezra Mount-Finette,  Nada Haidar, Fatima Adamu, Nirmal Ravi, Adam Thompson, Barry Heath, Sabine Dittrich, and Barry Finette. February 2022.

Full article here

2022 Trust in data-requesting organizations—A quantitative analysis on cultural antecedents and individual-level perceptions.

Clara Sophie Jenker, Nirmal Ravi, Marie Gabel, Jacqueline-Charlene Vogt. January, 2023

Full article here

2021 A Malaria Knowledge, Attitudes and Practice Survey in a Rural Community in Guinea

Erin Holsted, Barclay Kadiebwe, Amer Sattar, Abigail Salthouse, Nirmal Ravi. June, 2021

Full article here

2021 Survey of COVID-19 associated symptoms and reported deaths in an urban community in Kano, Nigeria

Disha Shahani, Zayyad Sani Farouq, Hadiza Galadima, Ashna Khare, Nirmal Ravi. June, 2021

Full article here

2021 Are all Thermometers Equal? A Study of Three Infrared Thermometers to Detect Fever in an African Outpatient Clinic

Nirmal Ravi, Mathura Vithyananthan, Aisha Amira Saidu. November, 2021

Full article here

2020 Electronic clinical decision support algorithms incorporating point-of-care diagnostic tests in low-resource settings: a target product profile.

Pellé KG, Rambaud-Althaus C, D'Acremont V, et alElectronic clinical decision support algorithms incorporating point-of-care diagnostic tests in low-resource settings: a target product profileBMJ Global Health 2020.

2019 Relationship Between a Typhoid Rapid Diagnostic Test and Clinical Symptoms Suggestive of Typhoid

11th International Conference on Typhoid and Other Invasive Salmonelloses, Hanoi, Vietnam, March 2019

2019 Assessing Rapid Diagnostic Test and Blood Smear Microscopy Outcomes with Malaria Diagnosis in Kano, Nigeria

American Society for Tropical Medicine and Hygiene, National Harbor, November, 2019

2019 Are All Thermometers Created Equal? A Study of Three Infrared Thermometers Vs Oral Electronic Thermometers to Detect Fever in an African Setting

Biomedical Engineering Society Annual Conference, Philadelphia, October, 2019

Our research projects

BMGF LLM Study
partners
Bill & Melinda Gates Foundation, Innovations for Poverty Action (IPA), World Bank Development Research Group, EHA Clinics REACH Program
dates
2023 - Present
Overview
This study is a pilot test of LLM augmentation of FHW decision-making in a clinical setting, in a research design that can mitigate any risks of the AI.The goal of this study is to develop and test scalable and cost-effective ways to use LLMs (such as GPT-4) to provide “second opinions” for health providers in low- and middle-income countries (LMICs).
Yemaachi - Northern Nigerian Cancer genome sequencing project.
partners
Yemaachi Biotechnology, Ghana; Aminu Kano Teaching Hospital, Kano; Federal Teaching Hospital, Katsina.
dates
2023 - Present
Overview
This is a partnership project between EHA Clinics and Yemaachi Biotech, a molecular research organization in Ghana. The project is a genetic Characterization of Breast, Prostate, Bladder, Endometrial, Colorectal Cancers and retinoblastoma in Northern Nigeria. The study sites are Aminu Kano Teaching Hospital Kano and Federal Teaching Hospital Katsina. EHA Clinics is coordinating the sample logistics and DNA preparation of the samples.
THINKMD-DIV-RCT
partners
ThinkMD, Innovations for Poverty Action (IPA), World Bank Development Research Group, Yale University, Washington State University
dates
2023 - Present
Overview
The primary goal of this study is to understand whether equipping minimally trained/non-trained government healthcare providers with an advanced clinical decision tool such as THINKMD MEDSINC leads them to perform clinical evaluations and determine appropriate care plans that resemble those of higher-skill providers such as doctors.
Pharmacoeconomic Study
partners
University of Michigan
dates
2022
Overview
In the quest to understand why the take-up of high-quality antimalarial, especially ACTs is low in Nigeria, EHA Clinics in collaboration with two Ph.D. students at the University of Michigan kick-started a Pilot study on “Information frictions, demand for quality, and welfare in the market for antimalarial”. The focus of the study is on the price difference between higher and lower-quality medicine, and whether people think vendors around them sell proper medicine.
JSI HEME Study
partners
USAID Advancing Nutrition Program, John Snow Inc., eHealth Africa
dates
2022
Overview
Along with research institutions from other continents; the American University of Beirut (Lebanon), Instituto Nutricional de Centroamérica y Panamá (Guatemala), the National Institute for Medical Research (Tanzania) and the University of British Columbia, EHA Clinics embarked on a Haemoglobin Measurement (HEME) Laboratory Validation Study in collaboration with eHealth Africa to identify the best procedures and methods for determining haemoglobin (Hb) concentration, and anaemia prevalence in population surveys. The HEME Project was sponsored by USAID’s Advancing Nutrition Grants program and led by the JSI Research & Training Institute, Inc. (JSI) and a consortium of partners focusing on improving nutritional status and health outcomes where the burden of malnutrition is highest and critically impacts on young children, their caregivers, and women of reproductive age (WRA).
Cold Chain Device Research
partners
Global Good
dates
2015 - Present
Overview
EHA Clinics partnered with Global Good to field-test 2 of their cold chain equipment projects and provide iterative improvement support. Equipment was tested in active health facilities and community-based health activities across Northern Nigeria.
Malaria RDT Interpretation with Computer Vision
partners
ThinkMD, eHealth Africa
dates
July 2020 - Dec 2020
Overview
400 million RDTs are administered worldwide each year for malaria, of which tens of millions are misadministered or misinterpreted. This is a field-based study to test the accuracy of Audere’s OpenRDT platform for automatic reading of malaria rapid diagnostic tests (mRDTs).